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KMID : 0352419950140030281
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Keimyung Medical Journal
1995 Volume.14 No. 3 p.281 ~ p.287
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Primary Leiomyosacoma of the Scalp
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Abstract
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Primary leiomyosarcoma of the skin is a very rare soft tissue sarcoma. The lesion appear as a single painful and tender subcutaneous nodule, and the area most frequently involved was the extremity. The diagnosis is made by only histologic
examination of
the lestion. Cutaneous type is more common and has a relatively benign biologic behavior compaired with more maligant subcutaneous type.
We experienced a case of primary subcutaneous leiomyosarcoma which developed in a 59-year-old female. Firm, nontender goose-gee sized tumor was present on the scalp. Microscopic finding was composed of irregular interlacing bunldes of atypical
smooth
muscle cell which have bizarre nuclei, 10-20 mitotic figures per 20 high power field. Wide local excision with partial osteotomy followed by 5 cycles of cyclophosphamide (750mg/㎡/day) and doxorubicin(75mg/㎡/day) combination chemotherapy and
4,500cGy
of local irradiation was performed. Local recurrence or systemic metastases was not noted four years after surgery.
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KEYWORD
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